Dr. Shayan Sharif
Research Overview
Dr. Shayan Sharif and his team focus on improving poultry health by studying immune responses to viral pathogens, including Marek’s disease and avian influenza. They examine T-cell–mediated immunity, the role of gut microbiota in disease resistance, and the impact of antibiotics and probiotics on immune development.
In their avian influenza vaccine project, the team developed a novel vaccine and tested early-life vaccination strategies, including in ovo administration. AI and modeling techniques were applied to simulate virus transmission through respiratory and oral-fecal routes, evaluate vaccine efficacy, and optimize vaccination strategies. These models also support a decision support system (DSS) for predicting outbreak risks and guiding interventions, improving both disease control and cost-effectiveness.
Research Keywords
Poultry immunology | Marek’s disease virus | Avian influenza | Chicken immune response | T cell regulation | Host–pathogen interactions | Intestinal microbiota | Probiotics and antibiotics | Animal health | Food system biosecurity | Vaccine Development | Data analytics for vaccine efficacy evaluation | AI-driven modeling
